MYOCARDIAL IMPACT OF NHE1 REGULATION BY SILDENAFIL

Myocardial Impact of NHE1 Regulation by Sildenafil

The cardiac Na+/H+ exchanger (NHE1) is a membrane glycoprotein fundamental for proper cell functioning due its multiple housekeeping tasks, including regulation of intracellular pH, Na+ concentration, and cell volume.In the heart, hyperactivation of NHE1 has been linked to the development of different pathologies.Several studies in animal models th

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Fitness Consequences of Innovation in Spotted Hyenas

Innovation is a well-studied cognitive phenomenon related to general intelligence and brain size.Innovative ability varies considerably within species and it is widely assumed that this variation must have important fitness consequences.However, direct evidence for a link between innovative ability and fitness has rarely been shown.Previous researc

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